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Table of Contents *
Introduction
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What is research?
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Why do we do research?
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Choosing a topic for research
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Types of Research Stu..
TK. 2070
Product Specification & Summary
Table of Contents *
Introduction
*
What is research?
*
Why do we do research?
*
Choosing a topic for research
*
Types of Research Studies
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Case control studies
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Cohort studies
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Cross sectional studies
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Randomized controlled trial
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Large simple clinical trials
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Descriptive studies
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Diagnostic tests
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Meta-analysis
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Multicentric trials
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New drug development ? Phase I to IV studies
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Planning and Design of a Study
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Hypothesis testing
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Study subjects or participants and recruitment, inclusion, exclusion criteria
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Statistical errors
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Power of a study
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Sample size calculations
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Interventions
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Bias and confounders
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End points
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Follow up
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Data collection and data management
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Statistical evaluation of data
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Funding
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Ethics in Research
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Evolution of ethics
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Participants? rights
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Ethics committees
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Ethics committee approval
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Applied Biostatistics
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Indispensability of statistics
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How much statistics does a clinician need to know?
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Population, sample and sample size
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Probability and odds
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Mean, median, mode
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Normal distribution
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Standard deviation, variance and standard error of mean *
Percentiles and quartiles
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P value
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Confidence intervals
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Measures of association?Association between two events, relative risk, risk ratio and odds ratio
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Risk measurements
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Correlation and correlation coefficient
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Regression analysis
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Survival analysis
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Choosing an appropriate statistical test
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Role of biostatistician
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Submitting a Paper for Publication
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Choosing the journal
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Submitting a research paper for publication
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The anatomy or structure of a scientific paper
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Submission of rejected paper to another journal
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Additional points
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Writing a case report
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Evidence Based Medicine (EBM)
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Importance of EBM
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Sources of evidence
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Evidence of efficiency as well as of safety
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Science of reading a journal and evaluating evidence
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Levels of evidence
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Presenting Papers at Meetings and Conferences
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Misdeeds and Misconduct in Research and Publication
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Misdeeds and misconduct
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Prevention of misconduct
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Registry of Clinical Trials
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Registry
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Registration of a study
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Good Clinical Practice (GCP) and Good Manufacturing Practice (GMP)
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Historical Glimpses of Research in Medicine
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Evolution of research methods
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Evolution of ethics in research
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Abbreviations
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Demystification of Technical Jargon
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Bibliography
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Index
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